Notice A Pattern? Enmity.

And I will put enmity between thee [the Serpent] and the woman, and between thy seed and her seed; it shall bruise thy head, and thou shalt bruise his heel. Genesis 3:15

And the dragon was wroth with the woman, and went to make war with the remnant of her seed, which keep the commandments of God, and have the testimony of Jesus Christ. Revelation 12:17

Jesus to Jewish leadership: O generation of vipers, how can ye, being evil, speak good things?  Matthew 12:34

Jesus to Jewish leadership: Ye serpents, ye generation of vipers, how can ye escape the damnation of hell? Matthew 23:33

And the great dragon was cast out, that old serpent, called the Devil, and Satan, which deceiveth the whole world: Rev 12:9

Ye adulterers and adulteresses, know ye not that the friendship of the world is enmity with God? whosoever therefore will be a friend of the world is the enemy of God. James 4:4